Understanding Monkeypox and How Outbreaks Spread

The Washington Post
Jul 05, 2022

Understanding Monkeypox and How Outbreaks Spread


The global eradication of smallpox more than 40 years ago was one of the greatest achievements in public-health history, vanquishing a cause of death, blindness and disfigurement that had plagued humanity for at least 3,000 years. But, on the downside, it also led to the end of a global vaccination program that provided protection against other pox viruses. That includes monkeypox, which has been spilling over from its animal hosts to infect humans in Africa with increasing frequency since the 1970s. Monkeypox now represents a serious, evolving threat after sparking outbreaks in dozens of countries this year, mostly in Europe, demonstrating again how readily an infectious agent that emerges in one country can quickly become an international concern.

1. What’s monkeypox?

Monkeypox is a misnomer resulting from the fact that it was first discovered at the Statens Serum Institut in Copenhagen in 1958, when outbreaks of a pox-like disease occurred in monkeys kept for research. While monkeys are susceptible to it, just like humans are, they aren’t the source. The virus belongs to the Orthopoxvirus genus, which includes the variola virus, the cause of smallpox; the vaccinia virus, which is used in the smallpox vaccine; and cowpox virus. Monkeypox is less contagious than smallpox and the symptoms are milder. About 30% of smallpox patients died, while the fatality rate for monkeypox in recent times is around 3% to 6%, according to the World Health Organization.