This film weaves together and amplifies the stories from individuals and groups intentionally leading change, wherever they are situated in their respective ‘system’. It reveals some of the many ways that these changemakers have managed to significantly impact their health care environments and improve health outcomes, often through relatively small, local interventions. Their experiences span subjects such as improving patient safety and reducing patient harm; preventing the death of newborns through a model that places parents at the centre of specialized care; transforming mental health programming; addressing the root causes of teenage suicide; saving the lives of babies born with anomalies; or promoting community health and introducing compassion in health leadership.