Leaders from across the world at the Eightieth United Nations General Assembly (UNGA) have adopted the political declaration to combat noncommunicable diseases (NCDs) and mental health challenges through a fully integrated approach. This is the outcome of the intergovernmental negotiations in advance of and considered by the fourth high-level meeting of the UNGA on the prevention and control of NCDs and the promotion of mental health and well-being, held on 25 September 2025.

Titled "Equity and integration: transforming lives and livelihoods through leadership and action on noncommunicable diseases and the promotion of mental health and well-being", the political declaration is the first such declaration addressing NCDs and mental health together, and marks a unique opportunity to accelerate global progress with a set of specific global targets for 2030. This step is expected to usher in a new era in addressing some of the world’s most pressing health challenges – affecting people of all ages and income levels across the globe.