People, animals, plants, ecosystems: making the case for investing in One Health

WHO
Aug 25, 2026

People, animals, plants, ecosystems: making the case for investing in One Health


The economic costs from zoonotic and other infectious diseases run into billions of US dollars annually.  

And according to World Bank estimates, antimicrobial resistance could lead to a loss of around 3.8% of global gross domestic product by 2050.

These global health threats and potential economic consequences mean that countries need to invest in new ways to increase preparedness and prevention.

A new brief from the Food and Agriculture Organization (FAO) Investment Centre, in collaboration with the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH), examines the long-term, added value of investing in One Health – an integrated approach that recognizes the connections between human, animal, plant and ecosystem health.

Financial and economic returns to investing in One Health: evidence and future directions looks at how the approach can reduce disease burdens, health-care costs, environmental contamination and antimicrobial resistance spread.

By promoting collaboration across sectors and disciplines, One Health helps maximize the impact of investments while reducing unintended consequences and improving long-term resilience.

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