Currently, patients must administer synthetic insulin up to 10 times a day to survive. The constant fluctuations between high and low blood sugar levels can cause short- and long-term physical health issues, and the effort to maintain stable levels can also affect mental health.
Researchers in the US, Australia, and China have designed novel smart insulins that remain dormant in the body and activate only when needed, mimicking the body's natural response to blood sugar changes. These glucose-responsive insulins (GRIs) stabilize blood sugar levels and prevent hyperglycemia and hypoglycemia by becoming active only when blood sugar levels are too high and inactive when levels drop too low. Experts believe that in the future, patients may only need insulin once a week.
