The 2017 research agenda defined five areas of work:
Stream 1. Reducing the risk of emergence of pandemic influenza
Stream 2. Limiting the spread of pandemic, zoonotic and seasonal epidemic influenza
Stream 3. Minimizing the impact of pandemic, zoonotic and seasonal epidemic influenza
Stream 4. Optimizing the treatment of patients
Stream 5. Promoting the development and application of modern public health tools
The recent COVID-19 pandemic, although due to a non-influenza virus, has broadened knowledge in areas of transmission, pharmaceutical interventions, and non-pharmaceutical measures. Meanwhile influenza virus has been constantly evolving causing epidemics in humans, spilling to new species, including mammals, such as the recent avian influenza outbreak in dairy cattle, and imposing pandemic threat to humans.
In this context, there is a pressing need to update the WHO Public Health Research Agenda for Influenza. To address the need, in early 2024 WHO established virtual work streams corresponding to the above defined Streams.