“Diabetes is a serious metabolic disorder characterized by sustained hyperglycemia, hyperinsulinemia, and hyperlipidemia due to insulin resistance, which potentially enhances the risk of cancer, especially triple-negative breast cancer (TNBC), the deadliest form of breast cancer. Diabetes and cancer are two major public health problems occurring mainly in the Pakistan, the causative link is yet to be proven, but the relative risks imparted by diabetes are said to be greatest (about two-fold or higher) for cancers of the liver, pancreas and endometrium, and less (about 1.2–1.5 fold) for cancers of the colon, rectum, breast and bladder.”