Against the backdrop of a protracted conflict, The Republic of Yemen faces complex and multifaceted development challenges that demand the country’s resources and attention. These challenges will worsen if the country remains vulnerable to extreme weather events and climate-related hazards. However, there is potential for the country to build long-term resilience to climate change and prevent current challenges from worsening. The objective of this Climate and Health Vulnerability Assessment (CHVA) is to assist decision-makers with planning adaptation measures to deal with the country’s climate-related health risks.