Sudan’s Federal Ministry of Health, with support from the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF), on 16 March launched round one of a nationwide vaccination campaign to urgently stop a new polio outbreak. Round one will run from 18 March 2023 for 4 days, with the second round following Ramadan in May, as vaccinators go door to door across the entire country to reach and protect an estimated 8.9 million children under 5 years.