Hepatitis B virus (HBV) infection is a leading cause of cirrhosis and liver cancer in the world. In a recent Morbidity and Mortality Weekly Report (MMWR) published by the United States Centers for Disease Control and Prevention (CDC), researchers report advancements made toward the elimination of mother-to-child transmission (MTCT) of HBV in the World Health Organization (WHO) African Region (AFR) between 2016 and 2021.