Chinese scientists have developed an atlas of high-throughput sequencing DNA damage and repair, which could help in promoting tumor prevention and treatment.

DNA damage and its improper repair are the major source of genomic alterations responsible for many human diseases, particularly cancer. However, a comprehensive database is still lacking despite the rapid accumulation of published datasets.

The researchers from the Center for Excellence in Molecular Cell Science, under the Chinese Academy of Sciences and Guangzhou Medical University, have presented the DNA Damage Atlas (DDA), which is the first large-scale repository of DNA damage and repair information.